Dengue Fever is a viral infection caused by one of four closely related viruses known as Dengue viruses. This illness is primarily transmitted through the bite of infected Aedes mosquitoes, particularly the Aedes aegypti species.

The virus enters the human body when an infected mosquito bites a person. Once inside, the virus replicates in various cells, including those lining the blood vessels, leading to flu-like symptoms such as high fever, severe headache, joint and muscle pain, nausea, and rash. These symptoms typically last for about 2-7 days but can vary in severity from mild to severe.

In some cases, Dengue Fever can progress to a more serious form called Dengue Hemorrhagic Fever (DHF), which can cause bleeding, organ failure, and even death if not promptly treated. DHF is more common in individuals who have previously been infected with a different serotype of the virus, as the antibodies produced during the first infection can interact with the virus in a way that worsens the disease.

Due to the lack of specific antiviral treatments, management of Dengue Fever focuses on relieving symptoms, maintaining fluid balance, and providing supportive care to affected individuals. Mosquito control measures, such as eliminating breeding sites and using insecticides, play a crucial role in preventing the spread of Dengue Fever.

Understanding the transmission dynamics and risk factors associated with Dengue Fever is essential for implementing effective control strategies and advancing vaccine development.