Explain Science

Lisinopril (Prinivil, Zestril)

Lisinopril, marketed under the brand names Prinivil and Zestril, is a medication classified as an ACE inhibitor (angiotensin-converting enzyme inhibitor). It is commonly prescribed to manage conditions such as hypertension (high blood pressure) and heart failure.

The drug works by blocking the activity of ACE, an enzyme responsible for the conversion of angiotensin I to angiotensin II. Angiotensin II is a potent vasoconstrictor, meaning it narrows blood vessels and increases blood pressure. By inhibiting ACE, Lisinopril helps to prevent the formation of angiotensin II, leading to the relaxation and dilation of blood vessels. This dilation allows blood to flow more easily, reducing blood pressure and improving circulation.

Lowering blood pressure helps to decrease the strain on the heart and arteries, which can help manage hypertension and reduce the risk of cardiovascular complications. Additionally, Lisinopril’s ability to relax blood vessels can be beneficial in conditions of heart failure, where the heart is weakened and struggles to pump effectively. By enhancing blood flow, Lisinopril helps relieve symptoms and improve overall heart function.

It’s important to follow the prescribed dosage and usage instructions, as Lisinopril may have potential side effects and interactions with other medications. Consulting a healthcare professional is essential to ensure optimal treatment and management of the prescribed condition.